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Structure of a spliceosome remodelled for exon ligation

Sebastian M. Fica (), Chris Oubridge, Wojciech P. Galej, Max E. Wilkinson, Xiao-Chen Bai, Andrew J. Newman and Kiyoshi Nagai ()
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Sebastian M. Fica: MRC Laboratory of Molecular Biology
Chris Oubridge: MRC Laboratory of Molecular Biology
Wojciech P. Galej: MRC Laboratory of Molecular Biology
Max E. Wilkinson: MRC Laboratory of Molecular Biology
Xiao-Chen Bai: MRC Laboratory of Molecular Biology
Andrew J. Newman: MRC Laboratory of Molecular Biology
Kiyoshi Nagai: MRC Laboratory of Molecular Biology

Nature, 2017, vol. 542, issue 7641, 377-380

Abstract: The cryo-electron microscopy structure of a yeast spliceosome stalled before mature RNA formation provides insight into the mechanism of exon ligation.

Date: 2017
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DOI: 10.1038/nature21078

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