Early brain development in infants at high risk for autism spectrum disorder

Heather Cody Hazlett (), Hongbin Gu, Brent C. Munsell, Sun Hyung Kim, Martin Styner, Jason J. Wolff, Jed T. Elison, Meghan R. Swanson, Hongtu Zhu, Kelly N. Botteron, D. Louis Collins, John N. Constantino, Stephen R. Dager, Annette M. Estes, Alan C. Evans, Vladimir S. Fonov, Guido Gerig, Penelope Kostopoulos, Robert C. McKinstry, Juhi Pandey, Sarah Paterson, John R. Pruett, Robert T. Schultz, Dennis W. Shaw, Lonnie Zwaigenbaum and Joseph Piven
Additional contact information
Heather Cody Hazlett: University of North Carolina
Hongbin Gu: University of North Carolina
Brent C. Munsell: College of Charleston
Sun Hyung Kim: University of North Carolina
Martin Styner: University of North Carolina
Jason J. Wolff: University of Minnesota
Jed T. Elison: Institute of Child Development, University of Minnesota
Meghan R. Swanson: Carolina Institute for Developmental Disabilities
Hongtu Zhu: University of North Carolina
Kelly N. Botteron: Washington University School of Medicine
D. Louis Collins: Montreal Neurological Institute, McGill University
John N. Constantino: Washington University School of Medicine
Stephen R. Dager: University of Washington
Annette M. Estes: Center on Human Development and Disability, University of Washington
Alan C. Evans: Montreal Neurological Institute, McGill University
Vladimir S. Fonov: Montreal Neurological Institute, McGill University
Guido Gerig: Tandon School of Engineering, New York University
Penelope Kostopoulos: Montreal Neurological Institute, McGill University
Robert C. McKinstry: Mallinckrodt Institute of Radiology, Washington University
Juhi Pandey: Center for Autism Research, The Children’s Hospital of Philadelphia and University of Pennsylvania
Sarah Paterson: Temple University
John R. Pruett: Washington University School of Medicine
Robert T. Schultz: Center for Autism Research, The Children’s Hospital of Philadelphia and University of Pennsylvania
Dennis W. Shaw: University of Washington
Lonnie Zwaigenbaum: University of Alberta
Joseph Piven: University of North Carolina

Nature, 2017, vol. 542, issue 7641, 348-351

Abstract: Surface area expansion from 6–12 months precedes brain overgrowth in high risk infants diagnosed with autism at 24 months and cortical features in the first year predict individual diagnostic outcomes.

Date: 2017
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DOI: 10.1038/nature21369

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