An atypical switch for metabolism and ageing
Colin Selman and
Dominic J. Withers ()
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Colin Selman: Colin Selman is at the Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow G12 8QQ, UK.
Dominic J. Withers: Dominic J. Withers is at the MRC London Institute of Medical Sciences, Imperial College London, London W12 0NN, UK.
Nature, 2017, vol. 542, issue 7641, 299-300
Abstract:
The enzyme S6K1 phosphorylates the enzyme glutamyl-prolyl tRNA synthetase to modulate metabolic activity and lifespan, revealing an atypical role for this synthetase as a target of a key metabolic signalling pathway. See Letter p.357
Date: 2017
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DOI: 10.1038/nature21500
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