The chronicles of T-cell exhaustion

Robert A. Amezquita () and Susan M. Kaech ()
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Robert A. Amezquita: Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Susan M. Kaech: Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Nature, 2017, vol. 543, issue 7644, 190-191

Abstract: T cells of the immune system often fail to target cancer cells because they enter a dysfunctional state known as exhaustion. Molecular analysis of T-cell exhaustion provides insights into the clinical use of these cells.

Date: 2017
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DOI: 10.1038/nature21508

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