Bone-derived hormone suppresses appetite

Richard D. Palmiter ()
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Richard D. Palmiter: Richard D. Palmiter is at the Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, USA.

Nature, 2017, vol. 543, issue 7645, 320-321

Abstract: The glycoprotein lipocalin 2 is released from the bones of mice in a nutrient-dependent manner and binds to receptors in the brain to suppress appetite. This is the first example of bone-derived signals mediating hunger. See Article p.385

Date: 2017
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DOI: 10.1038/nature21501

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