Effective combinatorial immunotherapy for castration-resistant prostate cancer

Xin Lu, James W. Horner, Erin Paul, Xiaoying Shang, Patricia Troncoso, Pingna Deng, Shan Jiang, Qing Chang, Denise J. Spring, Padmanee Sharma, John A. Zebala, Dean Y. Maeda, Y. Alan Wang () and Ronald A. DePinho ()
Additional contact information
Xin Lu: The University of Texas MD Anderson Cancer Center
James W. Horner: Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center
Erin Paul: Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center
Xiaoying Shang: The University of Texas MD Anderson Cancer Center
Patricia Troncoso: The University of Texas MD Anderson Cancer Center
Pingna Deng: The University of Texas MD Anderson Cancer Center
Shan Jiang: Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center
Qing Chang: Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center
Denise J. Spring: The University of Texas MD Anderson Cancer Center
Padmanee Sharma: The University of Texas MD Anderson Cancer Center
John A. Zebala: Syntrix Biosystems, Inc.
Dean Y. Maeda: Syntrix Biosystems, Inc.
Y. Alan Wang: The University of Texas MD Anderson Cancer Center
Ronald A. DePinho: The University of Texas MD Anderson Cancer Center

Nature, 2017, vol. 543, issue 7647, 728-732

Abstract: A new chimaeric mouse model of metastatic castration-resistant prostate cancer to efficiently test combination therapies in an autochthonous setting.

Date: 2017
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DOI: 10.1038/nature21676

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