Transmission of cytokinesis forces via E-cadherin dilution and actomyosin flows

Diana Pinheiro, Edouard Hannezo, Sophie Herszterg, Floris Bosveld, Isabelle Gaugue, Maria Balakireva, Zhimin Wang, Inês Cristo, Stéphane U. Rigaud, Olga Markova and Yohanns Bellaïche ()
Additional contact information
Diana Pinheiro: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Edouard Hannezo: Cavendish Laboratory, J. J. Thomson Avenue, University of Cambridge
Sophie Herszterg: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Floris Bosveld: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Isabelle Gaugue: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Maria Balakireva: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Zhimin Wang: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Inês Cristo: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Stéphane U. Rigaud: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Olga Markova: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934
Yohanns Bellaïche: Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934

Nature, 2017, vol. 545, issue 7652, 103-107

Abstract: Under physiological forces, resulting from cytokinesis, the mechanosensitivity of adherens junction arises from a local decrease in E-cadherin concentration and results in actomyosin flows.

Date: 2017
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DOI: 10.1038/nature22041

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