Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia

Ayuna Hattori, Makoto Tsunoda, Takaaki Konuma, Masayuki Kobayashi, Tamas Nagy, John Glushka, Fariba Tayyari, Daniel McSkimming, Natarajan Kannan, Arinobu Tojo, Arthur S. Edison and Takahiro Ito ()
Additional contact information
Ayuna Hattori: Franklin College of Arts and Sciences, The University of Georgia
Makoto Tsunoda: Graduate School of Pharmaceutical Sciences, The University of Tokyo
Takaaki Konuma: The Institute of Medical Science, The University of Tokyo
Masayuki Kobayashi: The Institute of Medical Science, The University of Tokyo
Tamas Nagy: College of Veterinary Medicine, The University of Georgia
John Glushka: Complex Carbohydrate Research Center, The University of Georgia
Fariba Tayyari: Franklin College of Arts and Sciences, The University of Georgia
Daniel McSkimming: Franklin College of Arts and Sciences, The University of Georgia
Natarajan Kannan: Franklin College of Arts and Sciences, The University of Georgia
Arinobu Tojo: The Institute of Medical Science, The University of Tokyo
Arthur S. Edison: Franklin College of Arts and Sciences, The University of Georgia
Takahiro Ito: Franklin College of Arts and Sciences, The University of Georgia

Nature, 2017, vol. 545, issue 7655, 500-504

Abstract: BCAT1, a cytosolic aminotransferase for branched-chain amino acids (BCAAs), is aberrantly activated and functionally required for disease progression in chronic myeloid leukaemia.

Date: 2017
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature22314 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:545:y:2017:i:7655:d:10.1038_nature22314

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature22314

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().