uORF-mediated translation allows engineered plant disease resistance without fitness costs

Guoyong Xu, Meng Yuan, Chaoren Ai, Lijing Liu, Edward Zhuang, Sargis Karapetyan, Shiping Wang and Xinnian Dong ()
Additional contact information
Guoyong Xu: Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Duke University
Meng Yuan: National Key Laboratory of Crop Genetic Improvement, National Centre of Plant Gene Research (Wuhan), Huazhong Agricultural University,
Chaoren Ai: National Key Laboratory of Crop Genetic Improvement, National Centre of Plant Gene Research (Wuhan), Huazhong Agricultural University,
Lijing Liu: Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Duke University
Edward Zhuang: Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Duke University
Sargis Karapetyan: Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Duke University
Shiping Wang: National Key Laboratory of Crop Genetic Improvement, National Centre of Plant Gene Research (Wuhan), Huazhong Agricultural University,
Xinnian Dong: Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Duke University

Nature, 2017, vol. 545, issue 7655, 491-494

Abstract: WebIn both laboratory and field studies, engineering translational control of immune mediator production in Arabidopsis and rice confers disease resistance, without compromising plant fitness.

Date: 2017
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DOI: 10.1038/nature22372

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