Signalling under the microscope
Ching-Ju Tsai (),
Joerg Standfuss () and
Robert M. Glaeser ()
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Ching-Ju Tsai: Laboratory of Biomolecular Research, Paul Scherrer Institute, Villigen PSI
Joerg Standfuss: Laboratory of Biomolecular Research, Paul Scherrer Institute, Villigen PSI
Robert M. Glaeser: University of California, Berkeley
Nature, 2017, vol. 546, issue 7656, 36-37
Abstract:
G-protein-coupled receptors are biological targets for drug discovery. Developments in cryo-electron microscopy have enabled the solution of the structure of a class B receptor in complex with its signalling protein. Two biologists and a microscopist explain the exciting implications of this work. See Article p.118
Date: 2017
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DOI: 10.1038/nature22491
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