Principles of early human development and germ cell program from conserved model systems

Toshihiro Kobayashi, Haixin Zhang, Walfred W. C. Tang, Naoko Irie, Sarah Withey, Doris Klisch, Anastasiya Sybirna, Sabine Dietmann, David A. Contreras, Robert Webb, Cinzia Allegrucci, Ramiro Alberio () and M. Azim Surani ()
Additional contact information
Toshihiro Kobayashi: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Haixin Zhang: School of Biosciences, University of Nottingham
Walfred W. C. Tang: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Naoko Irie: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Sarah Withey: School of Biosciences, University of Nottingham
Doris Klisch: School of Biosciences, University of Nottingham
Anastasiya Sybirna: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Sabine Dietmann: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
David A. Contreras: School of Biosciences, University of Nottingham
Robert Webb: School of Biosciences, University of Nottingham
Cinzia Allegrucci: School of Veterinary Medicine and Sciences, University of Nottingham
Ramiro Alberio: School of Biosciences, University of Nottingham
M. Azim Surani: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge

Nature, 2017, vol. 546, issue 7658, 416-420

Abstract: The authors trace the emergence of porcine primordial germ cells and develop in vitro models of primordial germ cell development from human and monkey pluripotent stem cells in order to provide insight into early human development.

Date: 2017
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DOI: 10.1038/nature22812

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