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Multilineage communication regulates human liver bud development from pluripotency

J. Gray Camp, Keisuke Sekine (), Tobias Gerber, Henry Loeffler-Wirth, Hans Binder, Malgorzata Gac, Sabina Kanton, Jorge Kageyama, Georg Damm, Daniel Seehofer, Lenka Belicova, Marc Bickle, Rico Barsacchi, Ryo Okuda, Emi Yoshizawa, Masaki Kimura, Hiroaki Ayabe, Hideki Taniguchi, Takanori Takebe () and Barbara Treutlein ()
Additional contact information
J. Gray Camp: Max Planck Institute for Evolutionary Anthropology
Keisuke Sekine: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Tobias Gerber: Max Planck Institute for Evolutionary Anthropology
Henry Loeffler-Wirth: Interdisciplinary Centre for Bioinformatics, Leipzig University
Hans Binder: Interdisciplinary Centre for Bioinformatics, Leipzig University
Malgorzata Gac: Max Planck Institute for Evolutionary Anthropology
Sabina Kanton: Max Planck Institute for Evolutionary Anthropology
Jorge Kageyama: Max Planck Institute for Evolutionary Anthropology
Georg Damm: University Hospital of Leipzig
Daniel Seehofer: University Hospital of Leipzig
Lenka Belicova: Max Planck Institute of Molecular Cell Biology and Genetics
Marc Bickle: Max Planck Institute of Molecular Cell Biology and Genetics
Rico Barsacchi: Max Planck Institute of Molecular Cell Biology and Genetics
Ryo Okuda: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Emi Yoshizawa: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Masaki Kimura: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Hiroaki Ayabe: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Hideki Taniguchi: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Takanori Takebe: Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
Barbara Treutlein: Max Planck Institute for Evolutionary Anthropology

Nature, 2017, vol. 546, issue 7659, 533-538

Abstract: Single-cell RNA sequencing analysis of two- and three-dimensional hepatic differentiation reveals that both systems recapitulate certain transcriptomic features of human hepatogenesis.

Date: 2017
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DOI: 10.1038/nature22796

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