Tracing the origins of relapse in acute myeloid leukaemia to stem cells

Liran I. Shlush, Amanda Mitchell, Lawrence Heisler, Sagi Abelson, Stanley W. K. Ng, Aaron Trotman-Grant, Jessie J. F. Medeiros, Abilasha Rao-Bhatia, Ivana Jaciw-Zurakowsky, Rene Marke, Jessica L. McLeod, Monica Doedens, Gary Bader, Veronique Voisin, ChangJiang Xu, John D. McPherson, Thomas J. Hudson, Jean C. Y. Wang, Mark D. Minden and John E. Dick ()
Additional contact information
Liran I. Shlush: Princess Margaret Cancer Centre, University Health Network
Amanda Mitchell: Princess Margaret Cancer Centre, University Health Network
Lawrence Heisler: Ontario Institute for Cancer Research
Sagi Abelson: Princess Margaret Cancer Centre, University Health Network
Stanley W. K. Ng: Princess Margaret Cancer Centre, University Health Network
Aaron Trotman-Grant: Princess Margaret Cancer Centre, University Health Network
Jessie J. F. Medeiros: Princess Margaret Cancer Centre, University Health Network
Abilasha Rao-Bhatia: Princess Margaret Cancer Centre, University Health Network
Ivana Jaciw-Zurakowsky: Princess Margaret Cancer Centre, University Health Network
Rene Marke: Laboratory of Pediatric Oncology, Radboud University Medical Center
Jessica L. McLeod: Princess Margaret Cancer Centre, University Health Network
Monica Doedens: Princess Margaret Cancer Centre, University Health Network
Gary Bader: University of Toronto
Veronique Voisin: Donnelly Centre for Cellular and Biomolecular Research
ChangJiang Xu: Donnelly Centre for Cellular and Biomolecular Research
John D. McPherson: Ontario Institute for Cancer Research
Thomas J. Hudson: Ontario Institute for Cancer Research
Jean C. Y. Wang: Princess Margaret Cancer Centre, University Health Network
Mark D. Minden: Princess Margaret Cancer Centre, University Health Network
John E. Dick: Princess Margaret Cancer Centre, University Health Network

Nature, 2017, vol. 547, issue 7661, 104-108

Abstract: Identification of the cell types from which relapse arises in acute myeloid leukaemia, by following leukaemia propagation from patient-derived leukaemia samples.

Date: 2017
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DOI: 10.1038/nature22993

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