Ribosomes are optimized for autocatalytic production

Shlomi Reuveni, Måns Ehrenberg and Johan Paulsson ()
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Shlomi Reuveni: HMS, Harvard University
Måns Ehrenberg: Uppsala University
Johan Paulsson: HMS, Harvard University

Nature, 2017, vol. 547, issue 7663, 293-297

Abstract: Abstract Many fine-scale features of ribosomes have been explained in terms of function, revealing a molecular machine that is optimized for error-correction, speed and control. Here we demonstrate mathematically that many less well understood, larger-scale features of ribosomes—such as why a few ribosomal RNA molecules dominate the mass and why the ribosomal protein content is divided into 55–80 small, similarly sized segments—speed up their autocatalytic production.

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:547:y:2017:i:7663:d:10.1038_nature22998

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DOI: 10.1038/nature22998

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