Synergy of synthesis, computation and NMR reveals correct baulamycin structures

Jingjing Wu, Paula Lorenzo, Siying Zhong, Muhammad Ali, Craig P. Butts (), Eddie L. Myers () and Varinder K. Aggarwal ()
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Jingjing Wu: School of Chemistry, University of Bristol
Paula Lorenzo: School of Chemistry, University of Bristol
Siying Zhong: School of Chemistry, University of Bristol
Muhammad Ali: School of Chemistry, University of Bristol
Craig P. Butts: School of Chemistry, University of Bristol
Eddie L. Myers: School of Chemistry, University of Bristol
Varinder K. Aggarwal: School of Chemistry, University of Bristol

Nature, 2017, vol. 547, issue 7664, 436-440

Abstract: Experimental and computed nuclear magnetic resonance data and an iterative synthetic strategy have revealed the correct structures of the baulamycins, potentially important antimicrobial compounds, allowing them to be chemically synthesized.

Date: 2017
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DOI: 10.1038/nature23265

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