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Complex cellular logic computation using ribocomputing devices

Alexander A. Green (), Jongmin Kim, Duo Ma, Pamela A. Silver, James J. Collins and Peng Yin ()
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Alexander A. Green: Wyss Institute for Biologically Inspired Engineering, Harvard University
Jongmin Kim: Wyss Institute for Biologically Inspired Engineering, Harvard University
Duo Ma: Biodesign Center for Molecular Design and Biomimetics, Biodesign Institute and School of Molecular Sciences, Arizona State University
Pamela A. Silver: Wyss Institute for Biologically Inspired Engineering, Harvard University
James J. Collins: Wyss Institute for Biologically Inspired Engineering, Harvard University
Peng Yin: Wyss Institute for Biologically Inspired Engineering, Harvard University

Nature, 2017, vol. 548, issue 7665, 117-121

Abstract: De-novo-designed RNA molecules are used to construct cellular computing devices that can implement complex logic functions.

Date: 2017
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DOI: 10.1038/nature23271

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