Stimulation of functional neuronal regeneration from Müller glia in adult mice

Nikolas L. Jorstad, Matthew S. Wilken, William N. Grimes, Stefanie G. Wohl, Leah S. VandenBosch, Takeshi Yoshimatsu, Rachel O. Wong, Fred Rieke and Thomas A. Reh ()
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Nikolas L. Jorstad: University of Washington
Matthew S. Wilken: University of Washington
William N. Grimes: University of Washington
Stefanie G. Wohl: University of Washington
Leah S. VandenBosch: University of Washington
Takeshi Yoshimatsu: University of Washington
Rachel O. Wong: University of Washington
Fred Rieke: University of Washington
Thomas A. Reh: University of Washington

Nature, 2017, vol. 548, issue 7665, 103-107

Abstract: Inhibition of histone deacetylation allows the transcription factor Ascl1 to bind to key gene loci in Müller glia and drive the functional generation of retinal neurons in adult mice.

Date: 2017
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DOI: 10.1038/nature23283

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