Rewiring the taste system

Hojoon Lee, Lindsey J. Macpherson, Camilo A. Parada, Charles S. Zuker () and Nicholas J. P. Ryba
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Hojoon Lee: Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
Lindsey J. Macpherson: Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
Camilo A. Parada: Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
Charles S. Zuker: Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
Nicholas J. P. Ryba: National Institute of Dental and Craniofacial Research, National Institutes of Health

Nature, 2017, vol. 548, issue 7667, 330-333

Abstract: Taste-receptor cells use distinct semaphorins to guide wiring of the peripheral taste system; targeted ectopic expression of SEMA3A or SEMA7A leads to bitter neurons responding to sweet tastes or sweet neurons responding to bitter tastes.

Date: 2017
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DOI: 10.1038/nature23299

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