Mitotic progression following DNA damage enables pattern recognition within micronuclei

Shane M. Harding, Joseph L. Benci, Jerome Irianto, Dennis E. Discher, Andy J. Minn and Roger A. Greenberg ()
Additional contact information
Shane M. Harding: Basser Center for BRCA, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania
Joseph L. Benci: Perelman School of Medicine, University of Pennsylvania
Jerome Irianto: Physical Sciences Oncology Center at Penn, 129 Towne Building, University of Pennsylvania
Dennis E. Discher: Physical Sciences Oncology Center at Penn, 129 Towne Building, University of Pennsylvania
Andy J. Minn: Perelman School of Medicine, University of Pennsylvania
Roger A. Greenberg: Basser Center for BRCA, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania

Nature, 2017, vol. 548, issue 7668, 466-470

Abstract: The authors report a link between mitosis, the formation of micronuclei and DNA-damage-induced cGAS-dependent inflammation.

Date: 2017
References: Add references at CitEc
Citations: View citations in EconPapers (14)

Downloads: (external link)
https://www.nature.com/articles/nature23470 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:548:y:2017:i:7668:d:10.1038_nature23470

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature23470

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().