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Putative medicines that mimic mutations

Sekar Kathiresan ()
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Sekar Kathiresan: Center for Genomic Medicine, Massachusetts General Hospital

Nature, 2017, vol. 548, issue 7669, 530-531

Abstract: Molecules that block the activity or production of the protein ANGPTL3 have now been found to lower blood levels of lipoproteins and cholesterol in mice and healthy humans, mimicking the protective effects of genetic mutations in ANGPTL3.

Date: 2017
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DOI: 10.1038/nature23544

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