Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep

Kai Liu, Juhyun Kim, Dong Won Kim, Yi Stephanie Zhang, Hechen Bao, Myrto Denaxa, Szu-Aun Lim, Eileen Kim, Chang Liu, Ian R. Wickersham, Vassilis Pachnis, Samer Hattar, Juan Song, Solange P. Brown and Seth Blackshaw ()
Additional contact information
Kai Liu: Johns Hopkins University School of Medicine
Juhyun Kim: Johns Hopkins University School of Medicine
Dong Won Kim: Johns Hopkins University School of Medicine
Yi Stephanie Zhang: Johns Hopkins University School of Medicine
Hechen Bao: University of North Carolina School of Medicine
Myrto Denaxa: The Francis Crick Institute
Szu-Aun Lim: University of North Carolina School of Medicine
Eileen Kim: Johns Hopkins University
Chang Liu: Johns Hopkins University School of Medicine
Ian R. Wickersham: The McGovern Institute for Brain Research, Massachusetts Institute of Technology
Vassilis Pachnis: The Francis Crick Institute
Samer Hattar: National Institute of Mental Health
Juan Song: University of North Carolina School of Medicine
Solange P. Brown: Johns Hopkins University School of Medicine
Seth Blackshaw: Johns Hopkins University School of Medicine

Nature, 2017, vol. 548, issue 7669, 582-587

Abstract: GABAergic Lhx6+ neurons in the ventral zona incerta promote both rapid eye movement and non-rapid eye movement sleep and inhibit the activity of wake-promoting GABAergic and Hcrt+ neurons of the lateral hypothalamus.

Date: 2017
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DOI: 10.1038/nature23663

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