Neuronal regulation of type 2 innate lymphoid cells via neuromedin U

Vânia Cardoso, Julie Chesné, Hélder Ribeiro, Bethania García-Cassani, Tânia Carvalho, Tiffany Bouchery, Kathleen Shah, Nuno L. Barbosa-Morais, Nicola Harris and Henrique Veiga-Fernandes ()
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Vânia Cardoso: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Julie Chesné: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Hélder Ribeiro: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Bethania García-Cassani: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Tânia Carvalho: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Tiffany Bouchery: Global Health Institute, École Polytechnique Fédérale de Lausanne (EPFL)
Kathleen Shah: Global Health Institute, École Polytechnique Fédérale de Lausanne (EPFL)
Nuno L. Barbosa-Morais: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Nicola Harris: Global Health Institute, École Polytechnique Fédérale de Lausanne (EPFL)
Henrique Veiga-Fernandes: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz

Nature, 2017, vol. 549, issue 7671, 277-281

Abstract: Group 2 innate lymphoid cells express the neuromedin U receptor 1 (NMUR1) and respond to neuromedin U (NMU) released by adjacent enteric neurons, and this interaction results in an enhanced immediate early response to the nematode Nippostrongylus brasiliensis.

Date: 2017
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DOI: 10.1038/nature23469

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