Division hierarchy leads to cell heterogeneity

Joan Seoane ()
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Joan Seoane: Vall d'Hebron Institute of Oncology, Vall d'Hebron Barcelona University Hospital Campus

Nature, 2017, vol. 549, issue 7671, 164-166

Abstract: Cellular diversity can hamper cancer treatment. Analysis of tumour cell-division patterns now reveals how such heterogeneity can arise by a hierarchical pattern of stem-cell divisions yielding a mosaic of different cells. See Article p.227

Date: 2017
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DOI: 10.1038/nature23546

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