m6A modulates haematopoietic stem and progenitor cell specification

Chunxia Zhang, Yusheng Chen, Baofa Sun, Lu Wang, Ying Yang, Dongyuan Ma, Junhua Lv, Jian Heng, Yanyan Ding, Yuanyuan Xue, Xinyan Lu, Wen Xiao, Yun-Gui Yang () and Feng Liu ()
Additional contact information
Chunxia Zhang: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Yusheng Chen: University of Chinese Academy of Sciences
Baofa Sun: CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, CAS Center for Excellence in Molecular Cell Science, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences
Lu Wang: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Ying Yang: CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, CAS Center for Excellence in Molecular Cell Science, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences
Dongyuan Ma: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Junhua Lv: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Jian Heng: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Yanyan Ding: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Yuanyuan Xue: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Xinyan Lu: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Wen Xiao: CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, CAS Center for Excellence in Molecular Cell Science, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences
Yun-Gui Yang: University of Chinese Academy of Sciences
Feng Liu: State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences

Nature, 2017, vol. 549, issue 7671, 273-276

Abstract: N6-methyladenosine modification of mRNA determines cell fate decisions during the specification of the first haematopoietic stem cells in zebrafish.

Date: 2017
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DOI: 10.1038/nature23883

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