Stereodivergent synthesis with a programmable molecular machine

Salma Kassem, Alan T. L. Lee, David A. Leigh (), Vanesa Marcos, Leoni I. Palmer and Simone Pisano
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Salma Kassem: School of Chemistry, University of Manchester
Alan T. L. Lee: School of Chemistry, University of Manchester
David A. Leigh: School of Chemistry, University of Manchester
Vanesa Marcos: School of Chemistry, University of Manchester
Leoni I. Palmer: School of Chemistry, University of Manchester
Simone Pisano: School of Chemistry, University of Manchester

Nature, 2017, vol. 549, issue 7672, 374-378

Abstract: A molecular machine that can be programmed to position a substrate at one of two directing sites on a molecule, which control the stereochemistry of addition to the substrate, demonstrates complexity, precision and function previously only observed in nature.

Date: 2017
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DOI: 10.1038/nature23677

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