A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis

Carlos Gorbea, Tim Mosbruger and Demián Cazalla ()
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Carlos Gorbea: University of Utah School of Medicine
Tim Mosbruger: Huntsman Cancer Institute, University of Utah School of Medicine
Demián Cazalla: University of Utah School of Medicine

Nature, 2017, vol. 550, issue 7675, 275-279

Abstract: Herpesvirus saimiri expresses a small nuclear RNA named HSUR2, with which it recruits two cellular microRNAs to repress specific mRNA targets and thereby inhibit apoptosis in infected T cells.

Date: 2017
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DOI: 10.1038/nature24034

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