Establishment of mouse expanded potential stem cells

Jian Yang, David J. Ryan, Wei Wang, Jason Cheuk-Ho Tsang, Guocheng Lan, Hideki Masaki, Xuefei Gao, Liliana Antunes, Yong Yu, Zhexin Zhu, Juexuan Wang, Aleksandra A. Kolodziejczyk, Lia S. Campos, Cui Wang, Fengtang Yang, Zhen Zhong, Beiyuan Fu, Melanie A. Eckersley-Maslin, Michael Woods, Yosuke Tanaka, Xi Chen, Adam C. Wilkinson, James Bussell, Jacqui White, Ramiro Ramirez-Solis, Wolf Reik, Berthold Göttgens, Sarah A. Teichmann, Patrick P. L. Tam, Hiromitsu Nakauchi, Xiangang Zou, Liming Lu and Pentao Liu ()
Additional contact information
Jian Yang: Wellcome Trust Sanger Institute
David J. Ryan: Wellcome Trust Sanger Institute
Wei Wang: Wellcome Trust Sanger Institute
Jason Cheuk-Ho Tsang: Wellcome Trust Sanger Institute
Guocheng Lan: Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre
Hideki Masaki: Institute of Medical Science, University of Tokyo
Xuefei Gao: Wellcome Trust Sanger Institute
Liliana Antunes: Wellcome Trust Sanger Institute
Yong Yu: Wellcome Trust Sanger Institute
Zhexin Zhu: Wellcome Trust Sanger Institute
Juexuan Wang: Wellcome Trust Sanger Institute
Aleksandra A. Kolodziejczyk: Wellcome Trust Sanger Institute
Lia S. Campos: Wellcome Trust Sanger Institute
Cui Wang: Wellcome Trust Sanger Institute
Fengtang Yang: Wellcome Trust Sanger Institute
Zhen Zhong: Medical Research Council Laboratory of Molecular Biology
Beiyuan Fu: Wellcome Trust Sanger Institute
Melanie A. Eckersley-Maslin: Epigenetics Programme, The Babraham Institute
Michael Woods: Wellcome Trust Sanger Institute
Yosuke Tanaka: Cambridge Institute for Medical Research, University of Cambridge
Xi Chen: Wellcome Trust Sanger Institute
Adam C. Wilkinson: Cambridge Institute for Medical Research, University of Cambridge
James Bussell: Wellcome Trust Sanger Institute
Jacqui White: Wellcome Trust Sanger Institute
Ramiro Ramirez-Solis: Wellcome Trust Sanger Institute
Wolf Reik: Wellcome Trust Sanger Institute
Berthold Göttgens: Cambridge Institute for Medical Research, University of Cambridge
Sarah A. Teichmann: Wellcome Trust Sanger Institute
Patrick P. L. Tam: Embryology Unit, Children’s Medical Research Institute, University of Sydney
Hiromitsu Nakauchi: Institute of Medical Science, University of Tokyo
Xiangang Zou: Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre
Liming Lu: Wellcome Trust Sanger Institute
Pentao Liu: Wellcome Trust Sanger Institute

Nature, 2017, vol. 550, issue 7676, 393-397

Abstract: Cultures of expanded potential stem cells can be established from individual eight-cell blastomeres, and by direct conversion of mouse embryonic stem cells and induced pluripotent stem cells, highlighting the feasibility of establishing expanded potential stem cells for other mammalian species.

Date: 2017
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DOI: 10.1038/nature24052

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