Single-molecule imaging reveals receptor–G protein interactions at cell surface hot spots

Titiwat Sungkaworn, Marie-Lise Jobin, Krzysztof Burnecki, Aleksander Weron, Martin J. Lohse and Davide Calebiro ()
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Titiwat Sungkaworn: Institute of Pharmacology and Toxicology, University of Würzburg
Marie-Lise Jobin: Institute of Pharmacology and Toxicology, University of Würzburg
Aleksander Weron: Faculty of Pure and Applied Mathematics, Hugo Steinhaus Center, Wroclaw University of Science and Technology
Martin J. Lohse: Institute of Pharmacology and Toxicology, University of Würzburg
Davide Calebiro: Institute of Pharmacology and Toxicology, University of Würzburg

Nature, 2017, vol. 550, issue 7677, 543-547

Abstract: G-protein-coupled receptors and their G protein partners are studied by single-molecule imaging in living cells, which reveals hot spots on the cell membrane where receptors and G proteins interact and signal.

Date: 2017
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DOI: 10.1038/nature24264

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