The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution

Modi Safra, Aldema Sas-Chen, Ronit Nir, Roni Winkler, Aharon Nachshon, Dan Bar-Yaacov, Matthias Erlacher, Walter Rossmanith, Noam Stern-Ginossar and Schraga Schwartz ()
Additional contact information
Modi Safra: Weizmann Institute of Science
Aldema Sas-Chen: Weizmann Institute of Science
Ronit Nir: Weizmann Institute of Science
Roni Winkler: Weizmann Institute of Science
Aharon Nachshon: Weizmann Institute of Science
Dan Bar-Yaacov: Weizmann Institute of Science
Matthias Erlacher: Biocenter Innsbruck, Medical University of Innsbruck
Walter Rossmanith: Center for Anatomy and Cell Biology, Medical University of Vienna
Noam Stern-Ginossar: Weizmann Institute of Science
Schraga Schwartz: Weizmann Institute of Science

Nature, 2017, vol. 551, issue 7679, 251-255

Abstract: Transcriptome-wide mapping of N1-methyladenosine (m1A) at single-nucleotide resolution reveals m1A to be scarce in cytoplasmic mRNA, to inhibit translation, and to be highly dynamic at a single site in a mitochondrial mRNA.

Date: 2017
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DOI: 10.1038/nature24456

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