A semi-synthetic organism that stores and retrieves increased genetic information

Yorke Zhang, Jerod L. Ptacin, Emil C. Fischer, Hans R. Aerni, Carolina E. Caffaro, Kristine San Jose, Aaron W. Feldman, Court R. Turner and Floyd E. Romesberg ()
Additional contact information
Yorke Zhang: The Scripps Research Institute
Jerod L. Ptacin: Synthorx, Inc.
Emil C. Fischer: The Scripps Research Institute
Hans R. Aerni: Synthorx, Inc.
Carolina E. Caffaro: Synthorx, Inc.
Kristine San Jose: Synthorx, Inc.
Aaron W. Feldman: The Scripps Research Institute
Court R. Turner: Synthorx, Inc.
Floyd E. Romesberg: The Scripps Research Institute

Nature, 2017, vol. 551, issue 7682, 644-647

Abstract: A modified Escherichia coli is used to demonstrate that semi-synthetic organisms can use non-natural hydrophobic base pairs to genetically encode for the incorporation of non-canonical amino acids into proteins.

Date: 2017
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DOI: 10.1038/nature24659

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