Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host

David Palesch, Steven E. Bosinger, Gregory K. Tharp, Thomas H. Vanderford, Mirko Paiardini, Ann Chahroudi, Zachary P. Johnson, Frank Kirchhoff, Beatrice H. Hahn, Robert B. Norgren, Nirav B. Patel, Donald L. Sodora, Reem A. Dawoud, Caro-Beth Stewart, Sara M. Seepo, R. Alan Harris, Yue Liu, Muthuswamy Raveendran, Yi Han, Adam English, Gregg W. C. Thomas, Matthew W. Hahn, Lenore Pipes, Christopher E. Mason, Donna M. Muzny, Richard A. Gibbs, Daniel Sauter, Kim Worley, Jeffrey Rogers and Guido Silvestri ()
Additional contact information
David Palesch: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Steven E. Bosinger: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Gregory K. Tharp: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Thomas H. Vanderford: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Mirko Paiardini: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Ann Chahroudi: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Zachary P. Johnson: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Frank Kirchhoff: Institute of Molecular Virology, Ulm University Medical Center
Beatrice H. Hahn: Perelman School of Medicine, University of Pennsylvania
Robert B. Norgren: Cell Biology and Anatomy, University of Nebraska, Medical Center
Nirav B. Patel: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Donald L. Sodora: Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle
Reem A. Dawoud: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
Caro-Beth Stewart: University at Albany-State University of New York
Sara M. Seepo: University at Albany-State University of New York
R. Alan Harris: Human Genome Sequencing Center, Baylor College of Medicine
Yue Liu: Human Genome Sequencing Center, Baylor College of Medicine
Muthuswamy Raveendran: Human Genome Sequencing Center, Baylor College of Medicine
Yi Han: Human Genome Sequencing Center, Baylor College of Medicine
Adam English: Human Genome Sequencing Center, Baylor College of Medicine
Gregg W. C. Thomas: Indiana University
Matthew W. Hahn: Indiana University
Lenore Pipes: Weill Cornell Medical College
Christopher E. Mason: Weill Cornell Medical College
Donna M. Muzny: Human Genome Sequencing Center, Baylor College of Medicine
Richard A. Gibbs: Human Genome Sequencing Center, Baylor College of Medicine
Daniel Sauter: Institute of Molecular Virology, Ulm University Medical Center
Kim Worley: Human Genome Sequencing Center, Baylor College of Medicine
Jeffrey Rogers: Human Genome Sequencing Center, Baylor College of Medicine
Guido Silvestri: Emory Vaccine Center and Yerkes National Primate Research Center, Emory University

Nature, 2018, vol. 553, issue 7686, 77-81

Abstract: Whole-genome sequencing and comparative genomic analysis of immune-related genes of Cercocebus atys and Macaca mulatta identify candidate genes, such as ICAM2 and TLR4, that may explain the AIDS resistance of C. atys.

Date: 2018
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DOI: 10.1038/nature25140

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