Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators

Nian Liu, Cameron H. Lee, Tomek Swigut, Edward Grow, Bo Gu, Michael C. Bassik () and Joanna Wysocka ()
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Nian Liu: Stanford School of Medicine, Stanford University
Cameron H. Lee: Stanford School of Medicine, Stanford University
Tomek Swigut: Stanford School of Medicine, Stanford University
Edward Grow: Stanford School of Medicine, Stanford University
Bo Gu: Stanford School of Medicine, Stanford University
Michael C. Bassik: Stanford School of Medicine, Stanford University
Joanna Wysocka: Stanford School of Medicine, Stanford University

Nature, 2018, vol. 553, issue 7687, 228-232

Abstract: The retrotransposition of L1 is controlled by functionally diverse genes at the transcriptional or post-transcriptional levels, and its silencing can lead to the downregulation of host gene expression.

Date: 2018
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DOI: 10.1038/nature25179

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