Opening of the human epithelial calcium channel TRPV6

Luke L. McGoldrick, Appu K. Singh, Kei Saotome, Maria V. Yelshanskaya, Edward C. Twomey, Robert A. Grassucci and Alexander I. Sobolevsky ()
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Luke L. McGoldrick: Columbia University
Appu K. Singh: Columbia University
Kei Saotome: Columbia University
Maria V. Yelshanskaya: Columbia University
Edward C. Twomey: Columbia University
Robert A. Grassucci: Columbia University
Alexander I. Sobolevsky: Columbia University

Nature, 2018, vol. 553, issue 7687, 233-237

Abstract: The cryo-electron microscopy structure of the calcium channel TRPV6 in its open and closed states demonstrates a novel gating mechanism involving an alanine hinge.

Date: 2018
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DOI: 10.1038/nature25182

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