High response rate to PD-1 blockade in desmoplastic melanomas

Zeynep Eroglu, Jesse M. Zaretsky, Siwen Hu-Lieskovan (), Dae Won Kim, Alain Algazi, Douglas B. Johnson, Elizabeth Liniker, Ben Kong, Rodrigo Munhoz, Suthee Rapisuwon, Pier Federico Gherardini, Bartosz Chmielowski, Xiaoyan Wang, I. Peter Shintaku, Cody Wei, Jeffrey A. Sosman, Richard W. Joseph, Michael A. Postow, Matteo S. Carlino, Wen-Jen Hwu, Richard A. Scolyer, Jane Messina, Alistair J. Cochran, Georgina V. Long and Antoni Ribas ()
Additional contact information
Zeynep Eroglu: University of California Los Angeles
Jesse M. Zaretsky: University of California Los Angeles
Siwen Hu-Lieskovan: University of California Los Angeles
Dae Won Kim: Moffitt Cancer Center and University of South Florida
Alain Algazi: University of California San Francisco
Douglas B. Johnson: Vanderbilt Ingram Cancer Center
Elizabeth Liniker: Melanoma Institute Australia
Ben Kong: Westmead Hospital
Rodrigo Munhoz: Memorial Sloan Kettering Cancer Center
Suthee Rapisuwon: Georgetown Lombardi Cancer Center
Pier Federico Gherardini: Parker Institute for Cancer Immunotherapy
Bartosz Chmielowski: University of California Los Angeles
Xiaoyan Wang: University of California Los Angeles
I. Peter Shintaku: University of California Los Angeles
Cody Wei: University of California Los Angeles
Jeffrey A. Sosman: Vanderbilt Ingram Cancer Center
Richard W. Joseph: Mayo Clinic
Michael A. Postow: Memorial Sloan Kettering Cancer Center
Matteo S. Carlino: Melanoma Institute Australia
Wen-Jen Hwu: The University of Texas-MD Anderson Cancer Center
Richard A. Scolyer: Melanoma Institute Australia
Jane Messina: Moffitt Cancer Center and University of South Florida
Alistair J. Cochran: University of California Los Angeles
Georgina V. Long: Melanoma Institute Australia
Antoni Ribas: University of California Los Angeles

Nature, 2018, vol. 553, issue 7688, 347-350

Abstract: Immune checkpoint blockade with anti-PD-1 or anti-PD-L1 agents produces a high response rate in patients with desmoplastic melanoma.

Date: 2018
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DOI: 10.1038/nature25187

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