Monitoring T cell–dendritic cell interactions in vivo by intercellular enzymatic labelling

Giulia Pasqual, Aleksey Chudnovskiy, Jeroen M. J. Tas, Marianna Agudelo, Lawrence D. Schweitzer, Ang Cui, Nir Hacohen and Gabriel D. Victora ()
Additional contact information
Giulia Pasqual: Laboratory of Lymphocyte Dynamics, The Rockefeller University
Aleksey Chudnovskiy: Laboratory of Lymphocyte Dynamics, The Rockefeller University
Jeroen M. J. Tas: Laboratory of Lymphocyte Dynamics, The Rockefeller University
Marianna Agudelo: Laboratory of Lymphocyte Dynamics, The Rockefeller University
Lawrence D. Schweitzer: Broad Institute of MIT and Harvard
Ang Cui: Broad Institute of MIT and Harvard
Nir Hacohen: Broad Institute of MIT and Harvard
Gabriel D. Victora: Laboratory of Lymphocyte Dynamics, The Rockefeller University

Nature, 2018, vol. 553, issue 7689, 496-500

Abstract: Interactions between receptors and ligands on immune cells are visualized in vivo and in vitro using an enzyme-tagged ligand that, when cells interact, leaves behind a detectable label on the receptor-expressing cell.

Date: 2018
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DOI: 10.1038/nature25442

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