Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties

Huan Bao, Debasis Das, Nicholas A. Courtney, Yihao Jiang, Joseph S. Briguglio, Xiaochu Lou, Daniel Roston, Qiang Cui, Baron Chanda and Edwin R. Chapman ()
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Huan Bao: University of Wisconsin–Madison
Debasis Das: University of Wisconsin–Madison
Nicholas A. Courtney: University of Wisconsin–Madison
Yihao Jiang: University of Wisconsin–Madison
Joseph S. Briguglio: University of Wisconsin–Madison
Xiaochu Lou: University of Wisconsin–Madison
Daniel Roston: University of Wisconsin
Qiang Cui: University of Wisconsin
Baron Chanda: University of Wisconsin–Madison
Edwin R. Chapman: University of Wisconsin–Madison

Nature, 2018, vol. 554, issue 7691, 260-263

Abstract: Analysis at high temporal and spatial resolution shows that the number and dynamics of SNARE proteins available during exocytosis determines the size and stability of fusion pores.

Date: 2018
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DOI: 10.1038/nature25481

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