Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

Yvette C. Wong, Daniel Ysselstein and Dimitri Krainc ()
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Yvette C. Wong: Northwestern University Feinberg School of Medicine
Daniel Ysselstein: Northwestern University Feinberg School of Medicine
Dimitri Krainc: Northwestern University Feinberg School of Medicine

Nature, 2018, vol. 554, issue 7692, 382-386

Abstract: Formation of inter-organelle contacts between mitochondria and lysosomes, regulated by lysosomal RAB7 GTP hydrolysis, allows for bidirectional regulation of mitochondrial and lysosomal dynamics.

Date: 2018
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DOI: 10.1038/nature25486

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