Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress

Morgane Macheret and Thanos D. Halazonetis ()
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Morgane Macheret: University of Geneva
Thanos D. Halazonetis: University of Geneva

Nature, 2018, vol. 555, issue 7694, 112-116

Abstract: Oncogene activation results in firing of ectopic origins of replication within transcribed genes, resulting in replication stress and genome instability.

Date: 2018
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DOI: 10.1038/nature25507

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