Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

William J. Zacharias, David B. Frank, Jarod A. Zepp, Michael P. Morley, Farrah A. Alkhaleel, Jun Kong, Su Zhou, Edward Cantu and Edward E. Morrisey ()
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William J. Zacharias: University of Pennsylvania
David B. Frank: Penn Center for Pulmonary Biology, University of Pennsylvania
Jarod A. Zepp: University of Pennsylvania
Michael P. Morley: University of Pennsylvania
Farrah A. Alkhaleel: University of Pennsylvania
Jun Kong: University of Pennsylvania
Su Zhou: University of Pennsylvania
Edward Cantu: University of Pennsylvania
Edward E. Morrisey: University of Pennsylvania

Nature, 2018, vol. 555, issue 7695, 251-255

Abstract: An evolutionarily conserved alveolar epithelial progenitor lineage that derives from alveolar type 2 cells is responsive to Wnt signalling and acts as a major facultative progenitor in regenerating the distal lung.

Date: 2018
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DOI: 10.1038/nature25786

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