The mechanism of eukaryotic CMG helicase activation

Max E. Douglas, Ferdos Abid Ali, Alessandro Costa and John F. X. Diffley ()
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Max E. Douglas: Chromosome Replication Laboratory, The Francis Crick Institute
Ferdos Abid Ali: Macromolecular Machines Laboratory, The Francis Crick Institute
Alessandro Costa: Macromolecular Machines Laboratory, The Francis Crick Institute
John F. X. Diffley: Chromosome Replication Laboratory, The Francis Crick Institute

Nature, 2018, vol. 555, issue 7695, 265-268

Abstract: In vitro experiments, using purified proteins and an assay that detects DNA unwinding, reveal the mechanism of activation of eukaryotic DNA replication.

Date: 2018
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DOI: 10.1038/nature25787

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