Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis

Kazumichi M. Nishida, Kazuhiro Sakakibara, Yuka W. Iwasaki, Hiromi Yamada, Ryo Murakami, Yukiko Murota, Takeshi Kawamura, Tatsuhiko Kodama, Haruhiko Siomi and Mikiko C. Siomi ()
Additional contact information
Kazumichi M. Nishida: Graduate School of Science, The University of Tokyo
Kazuhiro Sakakibara: Graduate School of Science, The University of Tokyo
Yuka W. Iwasaki: Keio University School of Medicine
Hiromi Yamada: Graduate School of Science, The University of Tokyo
Ryo Murakami: Graduate School of Science, The University of Tokyo
Yukiko Murota: Graduate School of Science, The University of Tokyo
Takeshi Kawamura: Proteomics Laboratory, Isotope Science Center, The University of Tokyo
Tatsuhiko Kodama: Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo
Haruhiko Siomi: Keio University School of Medicine
Mikiko C. Siomi: Graduate School of Science, The University of Tokyo

Nature, 2018, vol. 555, issue 7695, 260-264

Abstract: The biogenesis of piRNAs in the silkworm Bombyx is simpler than in Drosophila, with the exonucleases Trim and Nbr having no major role, and the endonuclease Zuc acting at the 3′ rather than the 5′ end.

Date: 2018
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DOI: 10.1038/nature25788

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