Optogenetic regulation of engineered cellular metabolism for microbial chemical production

Evan M. Zhao, Yanfei Zhang, Justin Mehl, Helen Park, Makoto A. Lalwani, Jared E. Toettcher () and José L. Avalos ()
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Evan M. Zhao: Hoyt Laboratory, Princeton University
Yanfei Zhang: Hoyt Laboratory, Princeton University
Justin Mehl: Hoyt Laboratory, Princeton University
Helen Park: Hoyt Laboratory, Princeton University
Makoto A. Lalwani: Hoyt Laboratory, Princeton University
Jared E. Toettcher: Department of Molecular Biology
José L. Avalos: Hoyt Laboratory, Princeton University

Nature, 2018, vol. 555, issue 7698, 683-687

Abstract: Finely tuned optogenetic control of engineered Saccharomyces cerevisiae enhances the biosynthesis of valuable products such as isobutanol in laboratory-scale fermenters.

Date: 2018
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DOI: 10.1038/nature26141

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