Superfast DNA replication causes damage in cancer cells

Annabel Quinet () and Alessandro Vindigni ()

Nature, 2018, vol. 559, issue 7713, 186-187

Abstract: Inhibitors of PARP proteins are used in cancer treatment. It emerges that PARP inhibitors exert their effect by accelerating DNA replication to a speed at which DNA damage occurs.

Keywords: Cancer; Molecular biology (search for similar items in EconPapers)
Date: 2018
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DOI: 10.1038/d41586-018-05501-6

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