Histidine metabolism boosts cancer therapy

Christian Frezza ()

Nature, 2018, vol. 559, issue 7715, 484-485

Abstract: Clinical use of the anticancer drug methotrexate can be limited by its high toxicity. It emerges that a diet rich in the amino acid histidine increases the effectiveness of methotrexate treatment and lowers toxicity in mice.

Keywords: Cancer; Medical research; Metabolism (search for similar items in EconPapers)
Date: 2018
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DOI: 10.1038/d41586-018-05573-4

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