Gene editing reveals the effect of thousands of variants in a key cancer gene

Stephen J. Chanock ()

Nature, 2018, vol. 562, issue 7726, 201-202

Abstract: Gene editing has now been used to introduce every possible single-nucleotide mutation into key protein-coding regions in the cancer-predisposition gene BRCA1, to identify the variants that are linked to cancer risk.

Keywords: Cancer; Genetics; Biotechnology (search for similar items in EconPapers)
Date: 2018
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DOI: 10.1038/d41586-018-06022-y

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