Transcriptional regulation of nitrogen-associated metabolism and growth

Allison Gaudinier, Joel Rodriguez-Medina, Lifang Zhang, Andrew Olson, Christophe Liseron-Monfils, Anne-Maarit Bågman, Jessica Foret, Shane Abbitt, Michelle Tang, Baohua Li, Daniel E. Runcie, Daniel J. Kliebenstein, Bo Shen, Mary J. Frank, Doreen Ware and Siobhan M. Brady ()
Additional contact information
Allison Gaudinier: University of California, Davis
Joel Rodriguez-Medina: University of California, Davis
Lifang Zhang: Cold Spring Harbor
Andrew Olson: Cold Spring Harbor
Christophe Liseron-Monfils: Cold Spring Harbor
Anne-Maarit Bågman: University of California, Davis
Jessica Foret: University of California, Davis
Shane Abbitt: DuPont Pioneer
Michelle Tang: University of California, Davis
Baohua Li: University of California, Davis
Daniel E. Runcie: University of California, Davis
Daniel J. Kliebenstein: University of California, Davis
Bo Shen: DuPont Pioneer
Mary J. Frank: DuPont Pioneer
Doreen Ware: Cold Spring Harbor
Siobhan M. Brady: University of California, Davis

Nature, 2018, vol. 563, issue 7730, 259-264

Abstract: Abstract Nitrogen is an essential macronutrient for plant growth and basic metabolic processes. The application of nitrogen-containing fertilizer increases yield, which has been a substantial factor in the green revolution1. Ecologically, however, excessive application of fertilizer has disastrous effects such as eutrophication2. A better understanding of how plants regulate nitrogen metabolism is critical to increase plant yield and reduce fertilizer overuse. Here we present a transcriptional regulatory network and twenty-one transcription factors that regulate the architecture of root and shoot systems in response to changes in nitrogen availability. Genetic perturbation of a subset of these transcription factors revealed coordinate transcriptional regulation of enzymes involved in nitrogen metabolism. Transcriptional regulators in the network are transcriptionally modified by feedback via genetic perturbation of nitrogen metabolism. The network, genes and gene-regulatory modules identified here will prove critical to increasing agricultural productivity.

Keywords: Transcription-factor Mutations; Lateral Root Length; Gini Correlation; Nitrogen-responsive Genes; Rosette Size (search for similar items in EconPapers)
Date: 2018
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Citations: View citations in EconPapers (2)

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DOI: 10.1038/s41586-018-0656-3

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