From discoveries in ageing research to therapeutics for healthy ageing

Judith Campisi, Pankaj Kapahi, Gordon J. Lithgow, Simon Melov, John C. Newman and Eric Verdin ()
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Judith Campisi: Buck Institute for Research on Aging
Pankaj Kapahi: Buck Institute for Research on Aging
Gordon J. Lithgow: Buck Institute for Research on Aging
Simon Melov: Buck Institute for Research on Aging
John C. Newman: Buck Institute for Research on Aging
Eric Verdin: Buck Institute for Research on Aging

Nature, 2019, vol. 571, issue 7764, 183-192

Abstract: Abstract For several decades, understanding ageing and the processes that limit lifespan have challenged biologists. Thirty years ago, the biology of ageing gained unprecedented scientific credibility through the identification of gene variants that extend the lifespan of multicellular model organisms. Here we summarize the milestones that mark this scientific triumph, discuss different ageing pathways and processes, and suggest that ageing research is entering a new era that has unique medical, commercial and societal implications. We argue that this era marks an inflection point, not only in ageing research but also for all biological research that affects the human healthspan.

Date: 2019
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Citations: View citations in EconPapers (18)

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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:571:y:2019:i:7764:d:10.1038_s41586-019-1365-2

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DOI: 10.1038/s41586-019-1365-2

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