Tumour metabolites hinder DNA repair

Lei-Lei Chen and Yue Xiong ()

Nature, 2020, vol. 582, issue 7813, 492-494

Abstract: Altered metabolism and genome instability are hallmarks of cancer. A mechanism now explains how three small molecules that accumulate in tumours connect abnormal metabolism to genomic problems by hindering DNA repair.

Keywords: Cancer; Metabolism (search for similar items in EconPapers)
Date: 2020
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DOI: 10.1038/d41586-020-01569-1

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