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Structural strains of misfolded tau protein define different diseases

Henning Stahlberg () and Roland Riek ()

Nature, 2021, vol. 598, issue 7880, 264-265

Abstract: In diseases called tauopathies, misfolded tau proteins form aggregates called fibrils. Fibrils from nine different tauopathies show that tau misfolds in many ways, enabling the diseases to be classified according to fibril structure.

Keywords: Neurodegeneration; Structural biology; Alzheimer's disease (search for similar items in EconPapers)
Date: 2021
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DOI: 10.1038/d41586-021-02611-6

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