Alzheimer’s risk variant APOE4 linked to myelin-assembly malfunction

Karl Carlström () and Gonçalo Castelo-Branco ()

Nature, 2022, vol. 611, issue 7937, 670-671

Abstract: People who carry a particular variant of the APOE gene are at increased risk of developing Alzheimer’s disease. It emerges that this might be due to decreased production of a fatty substance called myelin by oligodendrocyte cells.

Keywords: Neuroscience; Alzheimer's disease; Brain (search for similar items in EconPapers)
Date: 2022
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DOI: 10.1038/d41586-022-03371-7

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